Negative Thought Patterns: People with depression often experience persistent negative thinking, self-doubt, or feelings of worthlessness. These cognitive distortions can worsen symptoms over time.

Personality Traits: Individuals who are highly self-critical, perfectionistic, or prone to excessive worry may be more susceptible to depression.

Difficulty Coping with Stress: Those who struggle with emotional regulation or have difficulty managing stress may be at a higher risk of developing depression.

Family History: Individuals with a close relative (such as a parent or sibling) who has experienced depression may have a higher risk of developing it themselves.

Brain Chemistry & Function: Imbalances in neurotransmitters like serotonin, dopamine, and norepinephrine—chemicals that regulate mood—can contribute to depression.

Hormonal Changes: Fluctuations in hormones, such as during pregnancy, postpartum, menopause, or thyroid disorders, can also increase the risk of depression.

Traumatic Life Events: Experiences such as childhood abuse, neglect, the loss of a loved one, or severe stress can trigger depression.

Chronic Stress & Lifestyle: High-pressure jobs, financial struggles, or a lack of social support can increase vulnerability to depression.

Substance Use & Medications: Drug or alcohol abuse, as well as certain medications, can contribute to depressive symptoms or worsen existing depression.